Novel drug targets for Mycobacterium tuberculosis: 2-heterostyrylbenzimidazoles as inhibitors of cell wall protein synthesis

Novel drug targets for Mycobacterium tuberculosis: 2-heterostyrylbenzimidazoles as inhibitors of cell wall protein synthesis

Abstract Background Multi drug-resistant and mycobacterial infections are a major public health challenge, leading to high mortality and socioeconomic burdens through worldwide. Novel therapeutics are necessary to treat the drug resistant strains, since no new chemical entities are emerged in the la...

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Bibliographic Details
Main Authors: Mohana Rao Anguru, Ashok Kumar Taduri, Rama Devi Bhoomireddy, Malathi Jojula, Shravan Kumar Gunda
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Chemistry Central Journal
Subjects:
Benzimidazole
Green synthesis
Mycobacterium tuberculosis
Antibacterial activity
Molecular docking studies
Online Access:http://link.springer.com/article/10.1186/s13065-017-0295-z

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http://link.springer.com/article/10.1186/s13065-017-0295-z

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