Precision-cut kidney slices (PCKS) to study development of renal fibrosis and efficacy of drug targeting ex vivo

Precision-cut kidney slices (PCKS) to study development of renal fibrosis and efficacy of drug targeting ex vivo

Renal fibrosis is a serious clinical problem resulting in the greatest need for renal replacement therapy. No adequate preventive or curative therapy is available that could be clinically used to target renal fibrosis specifically. The search for new efficacious treatment strategies is therefore war...

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Bibliographic Details
Main Authors: Fariba Poosti, Bao Tung Pham, Dorenda Oosterhuis, Klaas Poelstra, Harry van Goor, Peter Olinga, Jan-Luuk Hillebrands
Format: Article
Language:English
Published: The Company of Biologists 2015-10-01
Series:Disease Models & Mechanisms
Subjects:
Drug targeting
Fibrosis
Kidney
Tissue slices
Online Access:http://dmm.biologists.org/content/8/10/1227

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