Increased expression of kynurenine aminotransferases mRNA in lymphocytes of patients with inflammatory bowel disease

Background: Complex interaction of genetic defects with environmental factors seems to play a substantial role in the pathogenesis of inflammatory bowel disease (IBD). Accumulating data implicate a potential role of disturbed tryptophan metabolism in IBD. Kynurenic acid (KYNA), a derivative of trypt...

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Bibliographic Details
Main Authors: Ewa Dudzińska, Kinga Szymona, Renata Kloc, Paulina Gil-Kulik, Tomasz Kocki, Małgorzata Świstowska, Jacek Bogucki, Janusz Kocki, Ewa M. Urbanska
Format: Article
Language:English
Published: SAGE Publishing 2019-10-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756284819881304