In vitro modeling of the neurovascular unit: advances in the field

In vitro modeling of the neurovascular unit: advances in the field

Abstract The blood–brain barrier (BBB) is a fundamental component of the central nervous system. Its functional and structural integrity is vital in maintaining the homeostasis of the brain microenvironment. On the other hand, the BBB is also a major hindering obstacle for the delivery of effective...

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Bibliographic Details
Main Authors: Aditya Bhalerao, Farzane Sivandzade, Sabrina Rahman Archie, Ekram Ahmed Chowdhury, Behnam Noorani, Luca Cucullo
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Fluids and Barriers of the CNS
Subjects:
Blood–brain barrier
Neurovascular unit
3D models
Microfluidics
Organoids
Brain microvasculature
Online Access:http://link.springer.com/article/10.1186/s12987-020-00183-7

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