In house reverse membrane hybridisation assay versus GenoType MTBDRplus and their performance to detect mutations in the genes rpoB, katG and inhA

In house reverse membrane hybridisation assay versus GenoType MTBDRplus and their performance to detect mutations in the genes rpoB, katG and inhA

Drug-resistant tuberculosis (TB) threatens global TB control and is a major public health concern in several countries. We therefore developed a multiplex assay (LINE-TB/MDR) that is able to identify the most frequent mutations related to rifampicin (RMP) and isoniazid (INH) resistance. The assay is...

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Bibliographic Details
Main Authors: Sergio Luiz Montego Ferreira Junior, Elis Regina Dalla Costa, Paula Gonçalves dos Santos, Harrison Magdinier Gomes, Marcia Susana Nunes Silva, Leonardo Souza Esteves, Martha Maria Oliveira, Raquel de Abreu Maschmann, Afrânio Lineu Kritski, Philip Noel Suffys, Maria Lucia Rosa Rossetti
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2014-06-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Mycobacterium tuberculosis
resistance
hybridisation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000300307&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000300307&lng=en&tlng=en

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