Comprehensive assessment of ECM turnover using serum biomarkers establishes PBC as a high-turnover autoimmune liver disease

Comprehensive assessment of ECM turnover using serum biomarkers establishes PBC as a high-turnover autoimmune liver disease

Background & Aims: Primary sclerosing cholangitis (PSC), primary biliary cholangitis (PBC) and autoimmune hepatitis (AIH) are phenotypically distinct autoimmune liver diseases that progress to cirrhosis and liver failure; however, their histological fibrosis distribution differs. We investig...

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Bibliographic Details
Main Authors: Mette Vesterhus, Mette Juul Nielsen, Johannes Roksund Hov, Francesca Saffioti, Tina Manon-Jensen, Diana Julie Leeming, Bjørn Moum, Kirsten Muri Boberg, Massimo Pinzani, Tom Hemming Karlsen, Morten Asser Karsdal, Douglas Thorburn
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:JHEP Reports
Subjects:
Biomarker
Fibrosis
Primary sclerosing cholangitis
Primary biliary cholangitis
PRO-C3
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555920301129

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