Quantification of Lung Fibrosis in IPF-Like Mouse Model and Pharmacological Response to Treatment by Micro-Computed Tomography

Quantification of Lung Fibrosis in IPF-Like Mouse Model and Pharmacological Response to Treatment by Micro-Computed Tomography

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive degenerative lung disease leading to respiratory failure and death. Although anti-fibrotic drugs are now available for treating IPF, their clinical efficacy is limited and lung transplantation remains the only modality to prolong survival...

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Bibliographic Details
Main Authors: Francesca Ruscitti, Francesca Ravanetti, Valeria Bertani, Luisa Ragionieri, Laura Mecozzi, Nicola Sverzellati, Mario Silva, Livia Ruffini, Valentina Menozzi, Maurizio Civelli, Gino Villetti, Franco Fabio Stellari
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
lung fibrosis
animal model
mice
bleomycin
micro-CT
Nintedanib
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01117/full

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