TGF-β suppression of HBV RNA through AID-dependent recruitment of an RNA exosome complex.

TGF-β suppression of HBV RNA through AID-dependent recruitment of an RNA exosome complex.

Transforming growth factor (TGF)-β inhibits hepatitis B virus (HBV) replication although the intracellular effectors involved are not determined. Here, we report that reduction of HBV transcripts by TGF-β is dependent on AID expression, which significantly decreases both HBV transcripts and viral DN...

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Bibliographic Details
Main Authors: Guoxin Liang, Guangyan Liu, Kouichi Kitamura, Zhe Wang, Sajeda Chowdhury, Ahasan Md Monjurul, Kousho Wakae, Miki Koura, Miyuki Shimadu, Kazuo Kinoshita, Masamichi Muramatsu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004780

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