A model of hematopoietic bone marrow apoptosis during growth factor deprivation in combination with a cytokine

Abstract Background The process by which blood cells are formed is referred to as hematopoiesis. This process involves a complex sequence of phases that blood cells must complete. During hematopoiesis, a small fraction of cells undergo cell death. Causes of cell death are dependent upon various fact...

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Bibliographic Details
Main Authors: Christina L. Mouser, Eliana S. Antoniou, Evros K. Vassiliou
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Theoretical Biology and Medical Modelling
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12976-018-0080-2