Three-Dimensional In Vitro Hydro- and Cryogel-Based Cell-Culture Models for the Study of Breast-Cancer Metastasis to Bone

Three-Dimensional In Vitro Hydro- and Cryogel-Based Cell-Culture Models for the Study of Breast-Cancer Metastasis to Bone

Bone is the most common site for breast-cancer invasion and metastasis, and it causes severe morbidity and mortality. A greater understanding of the mechanisms leading to bone-specific metastasis could improve therapeutic strategies and thus improve patient survival. While three-dimensional in vitro...

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Bibliographic Details
Main Authors: Laura J. Bray, Constanze Secker, Berline Murekatete, Jana Sievers, Marcus Binner, Petra B. Welzel, Carsten Werner
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Cancers
Subjects:
breast cancer
hydrogel
bone metastasis
osteoblasts
3D model
Online Access:http://www.mdpi.com/2072-6694/10/9/292

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