Synergism between dipyridamole and cisplatin in human breast cancer cells in vitro

Cisplatin is very effective in the treatment of metastatic breast cancer. However, the development of cellular resistance is a serious problem in cisplatin chemotherapy. In the present work, the effects of dipyridamole (DPM) on the cellular accumulation and cytotoxicity of cisplatin was studied in c...

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Bibliographic Details
Main Authors: Janice R. Perussi, Dina N. Paltoo, Veronica A. L. Toppin, Robert G. Canada
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2003-05-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422003000300010