Making gametes from alternate sources of stem cells: past, present and future

Making gametes from alternate sources of stem cells: past, present and future

Abstract Infertile couples including cancer survivors stand to benefit from gametes differentiated from embryonic or induced pluripotent stem (ES/iPS) cells. It remains challenging to convert human ES/iPS cells into primordial germ-like cells (PGCLCs) en route to obtaining gametes. Considerable succ...

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Bibliographic Details
Main Authors: Deepa Bhartiya, Sandhya Anand, Hiren Patel, Seema Parte
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Reproductive Biology and Endocrinology
Subjects:
Embryonic stem cells
Induced pluripotent stem cells
Very small embryonic-like stem cells
Mesenchymal stromal cells
Niche
Gametes
Online Access:http://link.springer.com/article/10.1186/s12958-017-0308-8

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