Successful Treatment of Liver Aspergilloma by Caspofungin Acetate First-Line Therapy in a Non-Immunocompromised Patient
Aspergillosis remains to be a life-threatening complication in immunocompromised patients. However, <em>Aspergillus</em> infection can be observed in non-immunocompromised individuals in rare cases. We report a case of liver aspergilloma in a chronic aplastic anemia patie...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-09-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/13/9/11063 |
Summary: | Aspergillosis remains to be a life-threatening complication in immunocompromised patients. However, <em>Aspergillus</em> infection can be observed in non-immunocompromised individuals in rare cases. We report a case of liver aspergilloma in a chronic aplastic anemia patient under relatively intact immune status. Therapeutic strategy for this rare condition was extensively discussed and caspofungin acetate single agent first-line therapy was applied after careful consideration. Encouraging clinical and radiologic improvements were achieved in response to the antifungal salvage. Our long-term follow-up study also revealed a favorable prognosis. Based on this experience, we suggest caspofungin acetate as first-line therapy for treatment plans of liver aspergilloma. |
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ISSN: | 1422-0067 |