Successful Treatment of Liver Aspergilloma by Caspofungin Acetate First-Line Therapy in a Non-Immunocompromised Patient

Aspergillosis remains to be a life-threatening complication in immunocompromised patients. However, <em>Aspergillus</em> infection can be observed in non-immunocompromised individuals in rare cases. We report a case of liver aspergilloma in a chronic aplastic anemia patie...

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Bibliographic Details
Main Authors: Hong-Juan Dong, Li-Jie Yang, Jian-Hong Wang, Yi Huan, Qing-Xian Bai
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:International Journal of Molecular Sciences
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Online Access:http://www.mdpi.com/1422-0067/13/9/11063
Description
Summary:Aspergillosis remains to be a life-threatening complication in immunocompromised patients. However, <em>Aspergillus</em> infection can be observed in non-immunocompromised individuals in rare cases. We report a case of liver aspergilloma in a chronic aplastic anemia patient under relatively intact immune status. Therapeutic strategy for this rare condition was extensively discussed and caspofungin acetate single agent first-line therapy was applied after careful consideration. Encouraging clinical and radiologic improvements were achieved in response to the antifungal salvage. Our long-term follow-up study also revealed a favorable prognosis. Based on this experience, we suggest caspofungin acetate as first-line therapy for treatment plans of liver aspergilloma.
ISSN:1422-0067