Setting up a Bioluminescence Resonance Energy Transfer high throughput screening assay to search for protein/protein interaction inhibitors in mammalian cells.

Each step of the cell life and its response or adaptation to its environment are mediated by a network of protein/protein interactions termed interactome. Our knowledge of this network keeps growing due to the development of sensitive techniques devoted to study these interactions. The bioluminescen...

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Bibliographic Details
Main Authors: Cyril eCouturier, Benoit eDeprez
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Endocrinology
Subjects:
PPI
HTS
RET
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00100/full

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