Comparison of membrane affinity-based method with size-exclusion chromatography for isolation of exosome-like vesicles from human plasma

Comparison of membrane affinity-based method with size-exclusion chromatography for isolation of exosome-like vesicles from human plasma

Abstract Background Plasma extracellular vesicles (EVs), especially exosome-like vesicles (ELVs), are being increasingly explored as a source of potential noninvasive disease biomarkers. The discovery of blood-based biomarkers associated with ELVs requires methods that isolate high yields of these E...

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Bibliographic Details
Main Authors: Ruzena Stranska, Laurens Gysbrechts, Jens Wouters, Pieter Vermeersch, Katarzyna Bloch, Daan Dierickx, Graciela Andrei, Robert Snoeck
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Journal of Translational Medicine
Subjects:
Extracellular vesicles
Exosomes-like vesicles
Biomarkers
Size-exclusion chromatography
exoEasy kit
Plasma
Online Access:http://link.springer.com/article/10.1186/s12967-017-1374-6

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