Accurate identification and quantification of commensal microbiota bound by host immunoglobulins

Abstract Background Identifying which taxa are targeted by immunoglobulins can uncover important host-microbe interactions. Immunoglobulin binding of commensal taxa can be assayed by sorting bound bacteria from samples and using amplicon sequencing to determine their taxonomy, a technique most widel...

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Bibliographic Details
Main Authors: Matthew A. Jackson, Claire Pearson, Nicholas E. Ilott, Kelsey E. Huus, Ahmed N. Hegazy, Jonathan Webber, B. Brett Finlay, Andrew J. Macpherson, Fiona Powrie, Lilian H. Lam
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Microbiome
Subjects:
IgA
Online Access:https://doi.org/10.1186/s40168-020-00992-w

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