Accurate identification and quantification of commensal microbiota bound by host immunoglobulins

Accurate identification and quantification of commensal microbiota bound by host immunoglobulins

Abstract Background Identifying which taxa are targeted by immunoglobulins can uncover important host-microbe interactions. Immunoglobulin binding of commensal taxa can be assayed by sorting bound bacteria from samples and using amplicon sequencing to determine their taxonomy, a technique most widel...

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Bibliographic Details
Main Authors: Matthew A. Jackson, Claire Pearson, Nicholas E. Ilott, Kelsey E. Huus, Ahmed N. Hegazy, Jonathan Webber, B. Brett Finlay, Andrew J. Macpherson, Fiona Powrie, Lilian H. Lam
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Microbiome
Subjects:
IgA
IgA-Seq
Gastrointestinal
Microbiome
Immunoglobulin
Immunology
Online Access:https://doi.org/10.1186/s40168-020-00992-w

Internet

https://doi.org/10.1186/s40168-020-00992-w

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