Luciferase-expressing Leishmania infantum allows the monitoring of amastigote population size, in vivo, ex vivo and in vitro.

Luciferase-expressing Leishmania infantum allows the monitoring of amastigote population size, in vivo, ex vivo and in vitro.

Here we engineered transgenic Leishmania infantum that express luciferase, the objectives being to more easily monitor in real time their establishment either in BALB/c mice--the liver and spleen being mainly studied-or in vitro. Whatever stationary phase L. infantum promastigotes population--wild t...

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Bibliographic Details
Main Authors: Grégory Michel, Bernard Ferrua, Thierry Lang, Madhavi P Maddugoda, Patrick Munro, Christelle Pomares, Emmanuel Lemichez, Pierre Marty
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3172198?pdf=render

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