CD4-CD8-αβ and γδ T cells display inflammatory and regulatory potentials during human tuberculosis.

CD4-CD8-αβ and γδ T cells display inflammatory and regulatory potentials during human tuberculosis.

T-cells play an important role controlling immunity against pathogens and therefore influence the outcome of human diseases. Although most T-lymphocytes co-express either CD4 or CD8, a smaller T-cell subset found the in the human peripheral blood that expresses the αβ or γδ T-cell-receptor (TCR) lac...

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Main Authors: Melina B Pinheiro, Lis R Antonelli, Renato Sathler-Avelar, Danielle M Vitelli-Avelar, Silvana Spindola-de-Miranda, Tânia M P D Guimarães, Andrea Teixeira-Carvalho, Olindo A Martins-Filho, Vicente P C P Toledo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3519797?pdf=render

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