Evaluation of T-activated proteins as recall antigens to monitor Epstein–Barr virus and human cytomegalovirus-specific T cells in a clinical trial setting

Evaluation of T-activated proteins as recall antigens to monitor Epstein–Barr virus and human cytomegalovirus-specific T cells in a clinical trial setting

Abstract Background Pools of overlapping synthetic peptides are routinely used for ex vivo monitoring of antigen-specific T-cell responses. However, it is rather unlikely that these peptides match those resulting from naturally processed antigens. T-activated proteins have been described as immunoge...

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Bibliographic Details
Main Authors: Nina Körber, Uta Behrends, Ulrike Protzer, Tanja Bauer
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Translational Medicine
Subjects:
EBV
HCMV
T cells
Recall antigens
Immune monitoring
Clinical trials
Online Access:http://link.springer.com/article/10.1186/s12967-020-02385-x

Internet

http://link.springer.com/article/10.1186/s12967-020-02385-x

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