The clinical implications of adult-onset henoch-schonelin purpura

The clinical implications of adult-onset henoch-schonelin purpura

<p>Abstract</p> <p>Henoch-Schonlein Purpura (HSP) is a small vessel vasculitis mediated by IgA-immune complex deposition. It is characterized by the clinical tetrad of non-thrombocytopenic palpable purpura, abdominal pain, arthritis and renal involvement. Pathologically, it can be...

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Main Authors: Chi David S, Youngberg George, Saleh Hana, Elshenawy Yasmin, Jithpratuck Warit, Krishnaswamy Guha
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Clinical and Molecular Allergy
Online Access:http://www.clinicalmolecularallergy.com/content/9/1/9
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spelling doaj-2eb91ce320144e8082e6c46ee96d0f1d2020-11-25T01:00:13ZengBMCClinical and Molecular Allergy1476-79612011-05-0191910.1186/1476-7961-9-9The clinical implications of adult-onset henoch-schonelin purpuraChi David SYoungberg GeorgeSaleh HanaElshenawy YasminJithpratuck WaritKrishnaswamy Guha<p>Abstract</p> <p>Henoch-Schonlein Purpura (HSP) is a small vessel vasculitis mediated by IgA-immune complex deposition. It is characterized by the clinical tetrad of non-thrombocytopenic palpable purpura, abdominal pain, arthritis and renal involvement. Pathologically, it can be considered a form of immune complex-mediated leukocytoclastic vasculitis (LCV) involving the skin and other organs. Though it primarily affects children (over 90% of cases), the occurrence in adults has been rarely reported. Management often involves the use of immunomodulatory or immune-suppressive regimens.</p> http://www.clinicalmolecularallergy.com/content/9/1/9
collection DOAJ
language English
format Article
sources DOAJ
author Chi David S
Youngberg George
Saleh Hana
Elshenawy Yasmin
Jithpratuck Warit
Krishnaswamy Guha
spellingShingle Chi David S
Youngberg George
Saleh Hana
Elshenawy Yasmin
Jithpratuck Warit
Krishnaswamy Guha
The clinical implications of adult-onset henoch-schonelin purpura
Clinical and Molecular Allergy
author_facet Chi David S
Youngberg George
Saleh Hana
Elshenawy Yasmin
Jithpratuck Warit
Krishnaswamy Guha
author_sort Chi David S
title The clinical implications of adult-onset henoch-schonelin purpura
title_short The clinical implications of adult-onset henoch-schonelin purpura
title_full The clinical implications of adult-onset henoch-schonelin purpura
title_fullStr The clinical implications of adult-onset henoch-schonelin purpura
title_full_unstemmed The clinical implications of adult-onset henoch-schonelin purpura
title_sort clinical implications of adult-onset henoch-schonelin purpura
publisher BMC
series Clinical and Molecular Allergy
issn 1476-7961
publishDate 2011-05-01
description <p>Abstract</p> <p>Henoch-Schonlein Purpura (HSP) is a small vessel vasculitis mediated by IgA-immune complex deposition. It is characterized by the clinical tetrad of non-thrombocytopenic palpable purpura, abdominal pain, arthritis and renal involvement. Pathologically, it can be considered a form of immune complex-mediated leukocytoclastic vasculitis (LCV) involving the skin and other organs. Though it primarily affects children (over 90% of cases), the occurrence in adults has been rarely reported. Management often involves the use of immunomodulatory or immune-suppressive regimens.</p>
url http://www.clinicalmolecularallergy.com/content/9/1/9
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