Early treatment with minocycline following stroke in rats improves functional recovery and differentially modifies responses of peri-infarct microglia and astrocytes

Early treatment with minocycline following stroke in rats improves functional recovery and differentially modifies responses of peri-infarct microglia and astrocytes

Abstract Background Altered neuronal connectivity in peri-infarct tissue is an important contributor to both the spontaneous recovery of neurological function that commonly develops after stroke and improvements in recovery that have been induced by experimental treatments in animal models. Microgli...

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Bibliographic Details
Main Authors: Wai Ping Yew, Natalia D. Djukic, Jaya S. P. Jayaseelan, Frederick R. Walker, Karl A. A. Roos, Timothy K. Chataway, Hakan Muyderman, Neil R. Sims
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Neuroinflammation
Subjects:
Stroke
Focal ischemia
Microglia
Astrocytes
Minocycline
Functional recovery
Online Access:http://link.springer.com/article/10.1186/s12974-018-1379-y

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