Small-Molecule Modulation of PPARs for the Treatment of Prevalent Vascular Retinal Diseases

Small-Molecule Modulation of PPARs for the Treatment of Prevalent Vascular Retinal Diseases

Vascular-related retinal diseases dramatically impact quality of life and create a substantial burden on the healthcare system. Age-related macular degeneration, diabetic retinopathy, and retinopathy of prematurity are leading causes of irreversible blindness. In recent years, the scientific communi...

Full description

Bibliographic Details
Main Authors:	Xiaozheng Dou, Adam S. Duerfeldt
Format:	Article
Language:	English
Published:	MDPI AG 2020-12-01
Series:	International Journal of Molecular Sciences
Subjects:	diabetic retinopathy age-related macular degeneration retinopathy of prematurity peroxisome proliferator-activated receptor drug discovery
Online Access:	https://www.mdpi.com/1422-0067/21/23/9251

Similar Items

Targeting non-coding RNAs for the treatment of retinal diseases
by: Juhyun Song, et al.
Published: (2021-06-01)

New insight into the role of the complement in the most common types of retinopathy-current literature review
by: Martyna Chrzanowska, et al.
Published: (2018-11-01)

Effects of major ozonated autohemotherapy in the treatment of dry age related macular degeneration: a randomized controlled clinical study
by: Emma Borrell, et al.
Published: (2012-12-01)

Evaluating peripheral retinal vascularization and rate of recurrence after intravitreal injection of ranibizumab as a primary treatment for retinopathy of prematurity
by: Mostafa M El Manhaly, et al.
Published: (2020-01-01)

Prevalence, Pattern and Risk Factors of Retinal Diseases Among an Elderly Population in Nepal: The Bhaktapur Retina Study
by: Thapa R, et al.
Published: (2020-07-01)

Diverse roles of macrophages in intraocular neovascular diseases: a review
by: Ye-Di Zhou, et al.
Published: (2017-12-01)

ATP and Adenosine in the Retina and Retinal Diseases
by: Shan-Shan Ye, et al.
Published: (2021-06-01)

Experimental histopathological study on retinal and renal cellular response to intravitreous antiangiogenic drugs
by: João Borges Fortes Filho, et al.
Published: (2014-06-01)

Research progress of LncRNA in retinal pigment epithelium associated retinal diseases
by: Zi-Yan Tang, et al.
Published: (2019-08-01)

Promotion effect and mechanism of Caspase-1 on microglia in retinal neovascularization in oxygen-induced retinopathy
by: Zhi-Cha Hu, et al.
Published: (2018-04-01)

Intravitreal Ranibizumab for Subfoveal Choroidal Neovascularization from Age-Related Macular Degeneration with Combined Severe Diabetic Retinopathy
by: So Young Han, et al.
Published: (2015-02-01)

Quercetin Mitigates Inflammatory Responses Induced by Vascular Endothelial Growth Factor in Mouse Retinal Photoreceptor Cells through Suppression of Nuclear Factor Kappa B
by: Minsup Lee, et al.
Published: (2017-11-01)

Factors Associated with Retinopathy of Prematurity in Hospitalized Preterm Infants in Sanandaj, Iran
by: Majid Mansouri, et al.
Published: (2016-09-01)

Variation in the vitreoretinal configuration of Stage 4 retinopathy of prematurity in photocoagulated and treatment naive eyes undergoing vitrectomy
by: Salil Sharad Gadkari, et al.
Published: (2017-01-01)

Prevailing clinical practices regarding screening for retinopathy of prematurity among pediatricians in India: A pilot survey
by: Saurabh Dileep Patwardhan, et al.
Published: (2011-01-01)

Photoreceptor glucose metabolism determines normal retinal vascular growth
by: Zhongjie Fu, et al.
Published: (2018-01-01)

The Intersection of Serine Metabolism and Cellular Dysfunction in Retinal Degeneration
by: Tirthankar Sinha, et al.
Published: (2020-03-01)

The results of diagnostic and treatment of patients with diabetic retinopathy and age-related macular degeneration at a diabetes type 2.
by: I. V. Vorobyova, et al.
Published: (2014-10-01)

The results of diagnostic and treatment of patients with diabetic retinopathy and age-related macular degeneration at a diabetes type 2.
by: I. V. Vorobyova, et al.
Published: (2014-10-01)

Anti-VEGF-Resistant Retinal Diseases: A Review of the Latest Treatment Options
by: Josh O. Wallsh, et al.
Published: (2021-04-01)

Association of Pro12Ala polymorphism of <i>PPAR-γ2</i> Gene and diabetic retinopathy in type 2 diabetes
by: Yong-Qing Liu, et al.
Published: (2013-06-01)

Structural sequelae and refractive outcome 1 year after laser treatment for type 1 prethreshold retinopathy of prematurity in Asian Indian eyes
by: Deeksha Katoch, et al.
Published: (2011-01-01)

Profile of asymmetrical retinopathy of prematurity in twins
by: Azad Rajvardhan, et al.
Published: (2010-01-01)

Barriers to timely presentation for appropriate care of retinopathy of prematurity in Odisha, Eastern India
by: Tapas Ranjan Padhi, et al.
Published: (2019-01-01)

Kinins and Their Receptors as Potential Therapeutic Targets in Retinal Pathologies
by: Rahmeh Othman, et al.
Published: (2021-07-01)

Retinal Fundus Image Analysis for Diagnosis of Glaucoma: A Comprehensive Survey
by: M. Caroline Viola Stella Mary, et al.
Published: (2016-01-01)

Real-world scenario of retinopathy of prematurity in Kerala
by: Anubhav Goyal, et al.
Published: (2017-01-01)

Nanotechnology in retinal drug delivery
by: Sibo Jiang, et al.
Published: (2018-06-01)

Is Coffee Consumption associated with Age-related Macular Degeneration and Diabetic Retinopathy?
by: Neelam Kumari
Published: (2014-03-01)

Causes and Three-year Incidence of Irreversible Visual Impairment in Jing-An District, Shanghai, China from 2010-2015
by: Fei Xia, et al.
Published: (2017-11-01)

Prevalence and risk factors of retinopathy of prematurity
by: Cut Badriah, et al.
Published: (2012-06-01)

Photobiomodulation for the treatment of retinal diseases: a review
by: Ivayla I. Geneva
Published: (2016-01-01)

Relationships between Hearing Loss and the Prevalences of Cataract, Glaucoma, Diabetic Retinopathy, and Age-Related Macular Degeneration in Korea
by: Joon Mo Kim, et al.
Published: (2019-07-01)

Association of pseudo-exotropia with true esotropia in cicatricial retinopathy of prematurity
by: Anin Sethi, et al.
Published: (2020-01-01)

Macular hole following successful stage 4B/stage 5 retinopathy of prematurity surgery
by: Ekta Rishi, et al.
Published: (2019-01-01)

Are Anti-Retinal Autoantibodies a Cause or a Consequence of Retinal Degeneration in Autoimmune Retinopathies?
by: Grazyna Adamus
Published: (2018-04-01)

Fluorescein angiography of retinal vascular involution after intravitreal injection of ranibizumab for retinopathy of prematurity
by: Yong Cheng, et al.
Published: (2019-01-01)

Retinopathy Phenotypes in Type 2 Diabetes with Different Risks for Macular Edema and Proliferative Retinopathy
by: Ines P. Marques, et al.
Published: (2020-05-01)

Insights into the growing popularity of artificial intelligence in ophthalmology
by: Sreetama Dutt, et al.
Published: (2020-01-01)

The modern view on the concept of treatment of active stages of retinopathy of prematurity
by: A. V. Tereshchenko, et al.
Published: (2014-07-01)

Cannot write session to /tmp/vufind_sessions/sess_ejbtdqna59q5eet734b44bko9t