A human polymorphism affects NEDD4L subcellular targeting by leading to two isoforms that contain or lack a C2 domain
<p>Abstract</p> <p>Background</p> <p>Ubiquitination serves multiple cellular functions, including proteasomal degradation and the control of stability, function, and intracellular localization of a wide variety of proteins. NEDD4L is a member of the HECT class of E3 ubi...
Main Authors: | Lalouel Jean-Marc, Weiss Robert B, Blazer-Yost Bonnie L, Garrone Nicholas F, Rohrwasser Andreas |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-04-01
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Series: | BMC Cell Biology |
Online Access: | http://www.biomedcentral.com/1471-2121/10/26 |
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