DETERMINATION OF GAMMA - AMINOBUTYRIC ACID BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY

DETERMINATION OF GAMMA - AMINOBUTYRIC ACID BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY

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Gamma-aminobutyric acid is the main inhibitory amino acid neurotransmitter in several areas of the brain. Measurement of gamma-aminobutyric acid in the brain will help elucidate its metabolic rote and diagnostic value. The liquid chromatography (LC) system consisted of a delivery pump. Male rats (15...

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Main Author: D. Qujeq
Format: Article
Language:English
Published: Tehran University of Medical Sciences 1998-08-01
Series:Acta Medica Iranica
Subjects:
neurotransmitter
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4874.pdf&manuscript_id=4874
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spelling doaj-2e781b47289b4533b6afbeebc678f7f12020-11-25T03:42:52ZengTehran University of Medical SciencesActa Medica Iranica0044-60251998-08-01362102105DETERMINATION OF GAMMA - AMINOBUTYRIC ACID BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHYD. QujeqGamma-aminobutyric acid is the main inhibitory amino acid neurotransmitter in several areas of the brain. Measurement of gamma-aminobutyric acid in the brain will help elucidate its metabolic rote and diagnostic value. The liquid chromatography (LC) system consisted of a delivery pump. Male rats (150-250g) were used in this study. The brain was rapidly removed from decapitated animals. Trie chromatograms showed satisfactory resolution and symmetrical peak shapes, both with the standard and tissue extracts. the retention lime was 4.60 min. it was constant in repeated analyses and exactly the same for the standard and tissue samples. http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4874.pdf&manuscript_id=4874neurotransmitter
collection DOAJ
language English
format Article
sources DOAJ
author D. Qujeq
spellingShingle D. Qujeq
DETERMINATION OF GAMMA - AMINOBUTYRIC ACID BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY
Acta Medica Iranica
neurotransmitter
author_facet D. Qujeq
author_sort D. Qujeq
title DETERMINATION OF GAMMA - AMINOBUTYRIC ACID BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY
title_short DETERMINATION OF GAMMA - AMINOBUTYRIC ACID BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY
title_full DETERMINATION OF GAMMA - AMINOBUTYRIC ACID BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY
title_fullStr DETERMINATION OF GAMMA - AMINOBUTYRIC ACID BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY
title_full_unstemmed DETERMINATION OF GAMMA - AMINOBUTYRIC ACID BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY
title_sort determination of gamma - aminobutyric acid by high-performance liquid chromatography
publisher Tehran University of Medical Sciences
series Acta Medica Iranica
issn 0044-6025
publishDate 1998-08-01
description Gamma-aminobutyric acid is the main inhibitory amino acid neurotransmitter in several areas of the brain. Measurement of gamma-aminobutyric acid in the brain will help elucidate its metabolic rote and diagnostic value. The liquid chromatography (LC) system consisted of a delivery pump. Male rats (150-250g) were used in this study. The brain was rapidly removed from decapitated animals. Trie chromatograms showed satisfactory resolution and symmetrical peak shapes, both with the standard and tissue extracts. the retention lime was 4.60 min. it was constant in repeated analyses and exactly the same for the standard and tissue samples.
topic neurotransmitter
url http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4874.pdf&manuscript_id=4874
work_keys_str_mv AT dqujeq determinationofgammaaminobutyricacidbyhighperformanceliquidchromatography
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