Studies on the Synthesis of Vitamin D Analogs with Aromatic D-Ring

ABSTRACT Herein, we describe our studies on the synthesis of 1α,25-dihydroxyvitamin D3 analogs possessing a benzene ring replacing the natural 5-membered D-ring by the Wittig-Horner and dienyne approaches. A key feature is the synthesis of a Cr(CO)3-complexed previtamin D derivative that enables the...

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Bibliographic Details
Main Authors: SILVINA EDUARDO-CANOSA, MARÍA MARCO, RITA SIGÜEIRO, ANTONIO MOURIÑO
Format: Article
Language:English
Published: Academia Brasileira de Ciências
Series:Anais da Academia Brasileira de Ciências
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000301035&lng=en&tlng=en