Alcohol-associated intestinal dysbiosis impairs pulmonary host defense against Klebsiella pneumoniae.

Alcohol-associated intestinal dysbiosis impairs pulmonary host defense against Klebsiella pneumoniae.

Chronic alcohol consumption perturbs the normal intestinal microbial communities (dysbiosis). To investigate the relationship between alcohol-mediated dysbiosis and pulmonary host defense we developed a fecal adoptive transfer model, which allows us to investigate the impact of alcohol-induced gut d...

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Bibliographic Details
Main Authors: Derrick R Samuelson, Judd E Shellito, Vincent J Maffei, Eric D Tague, Shawn R Campagna, Eugene E Blanchard, Meng Luo, Christopher M Taylor, Martin J J Ronis, Patricia E Molina, David A Welsh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5481032?pdf=render

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