Dual role of TRBP in HIV replication and RNA interference: viral diversion of a cellular pathway or evasion from antiviral immunity?

<p>Abstract</p> <p>Increasing evidence indicates that RNA interference (RNAi) may be used to provide antiviral immunity in mammalian cells. Human micro (mi)RNAs can inhibit the replication of a primate virus, whereas a virally-encoded miRNA from HIV inhibits its own replication. In...

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Bibliographic Details
Main Authors: Clerzius Guerline, Lainé Sébastien, Gatignol Anne
Format: Article
Language:English
Published: BMC 2005-10-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/2/1/65