Engineering the yeast <it>Yarrowia lipolytica</it> for the production of therapeutic proteins homogeneously glycosylated with Man<sub>8</sub>GlcNAc<sub>2</sub> and Man<sub>5</sub>GlcNAc<sub>2</sub>

Engineering the yeast <it>Yarrowia lipolytica</it> for the production of therapeutic proteins homogeneously glycosylated with Man<sub>8</sub>GlcNAc<sub>2</sub> and Man<sub>5</sub>GlcNAc<sub>2</sub>

<p>Abstract</p> <p>Background</p> <p>Protein-based therapeutics represent the fastest growing class of compounds in the pharmaceutical industry. This has created an increasing demand for powerful expression systems. Yeast systems are widely used, convenient and cost-eff...

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Bibliographic Details
Main Authors: De Pourcq Karen, Vervecken Wouter, Dewerte Isabelle, Valevska Albena, Van Hecke Annelies, Callewaert Nico
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/11/1/53

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http://www.microbialcellfactories.com/content/11/1/53

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