More caution needs in study design and method selection for “In vitro antibacterial effect of Deconex and sodium hypochlorite against bacterial taxa isolated from dental units” [Letter]

• Main Authors: Emami A, Pirbonyeh N, Javanmardi F
• Format: Article
• Language: English
• Published: Dove Medical Press 2019-08-01
• Series: Infection and Drug Resistance
• Subjects: Deconex; sodium hypochlorite; dental units;
• Online Access: https://www.dovepress.com/more-caution-needs-in-study-design-and-method-selection-for-in-vitro-peer-reviewed-article-IDR

Amir Emami, Neda Pirbonyeh, Fatemeh JavanmardiDepartment of Microbiology, Burn and Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Fars, IranCorrespondence: Amir EmamiDepartment of Microbiology, Burn and Wound Healing Research Center, Amir-Al-Momenin Burn and Wound Healing Hospital, Shiraz University of Medical Sciences, Shiraz, Fars, PO Box 719875436, IranEmail [e-mail] Recently, we have meticulously read the paper by Amin et al1 about the effect of Deconex and sodium hypochlorite on bacterial taxa isolated from dental faculty units in Ahvaz Jundishapure University of Medical Sciences. Firstly, we are fortunate that a specialist evaluates axiomatic fact. According to the confirmed antimicrobial effect of deconex product by Borer Chemie AG based on its certificates (VAH: German Association for Applied Hygiene, CE1250 by Switzerland and EC-certificate by registration number 33818),2 no more tests are needed for confirmation, especially by non-specialized sections. These tests are merely administered by oversight organizations such as Food and Drug Administration (FDA) or infection control committee of Ministry of Health and Medical Education from approved and specialized laboratories. Currently, according to the categories of international FDA, alcoholic-based compounds are approved to be used as safe disinfectants especially in moderate conditions (not high-dose infections). Accordingly, it would be baseless to verify such compounds. Based on obvious data and the mechanism of alcoholic compounds on microbial proteins, no valid reports have been recently submitted about the formation of resistance against alcoholic-based disinfectants, not even in prolonged applications.3View the original paper by Amin and colleagues