Formation of the Imidazolinone Ring Under Mild Conditions in the Presence of Sodium Hydride

Substituted imidazolinones containing heterocyclic carboxylic acids as substituents and possessing herbicidal properties were synthesized by cyclization of 2-amino-2,3-dimethylbutyramide with heterocyclic ethyl dicarboxylates under mild conditions. The use of NaH as base leads to a significant incre...

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Bibliographic Details
Main Authors: Anibal J. Mocchi, Julio D. Fernandez, Antonio F. Lopez, Aleksey N. Vasiliev
Format: Article
Language:English
Published: MDPI AG 2004-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/9/7/535/
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spelling doaj-2e59717b375a408a9e057e6fd33850172020-11-24T22:22:26ZengMDPI AGMolecules1420-30492004-06-019753554010.3390/90700535Formation of the Imidazolinone Ring Under Mild Conditions in the Presence of Sodium HydrideAnibal J. MocchiJulio D. FernandezAntonio F. LopezAleksey N. VasilievSubstituted imidazolinones containing heterocyclic carboxylic acids as substituents and possessing herbicidal properties were synthesized by cyclization of 2-amino-2,3-dimethylbutyramide with heterocyclic ethyl dicarboxylates under mild conditions. The use of NaH as base leads to a significant increase in the reaction rate and allows the preparation of the target compounds in high yields.http://www.mdpi.com/1420-3049/9/7/535/Imidazolinonesherbicidescyclizationsodium hydride
collection DOAJ
language English
format Article
sources DOAJ
author Anibal J. Mocchi
Julio D. Fernandez
Antonio F. Lopez
Aleksey N. Vasiliev
spellingShingle Anibal J. Mocchi
Julio D. Fernandez
Antonio F. Lopez
Aleksey N. Vasiliev
Formation of the Imidazolinone Ring Under Mild Conditions in the Presence of Sodium Hydride
Molecules
Imidazolinones
herbicides
cyclization
sodium hydride
author_facet Anibal J. Mocchi
Julio D. Fernandez
Antonio F. Lopez
Aleksey N. Vasiliev
author_sort Anibal J. Mocchi
title Formation of the Imidazolinone Ring Under Mild Conditions in the Presence of Sodium Hydride
title_short Formation of the Imidazolinone Ring Under Mild Conditions in the Presence of Sodium Hydride
title_full Formation of the Imidazolinone Ring Under Mild Conditions in the Presence of Sodium Hydride
title_fullStr Formation of the Imidazolinone Ring Under Mild Conditions in the Presence of Sodium Hydride
title_full_unstemmed Formation of the Imidazolinone Ring Under Mild Conditions in the Presence of Sodium Hydride
title_sort formation of the imidazolinone ring under mild conditions in the presence of sodium hydride
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2004-06-01
description Substituted imidazolinones containing heterocyclic carboxylic acids as substituents and possessing herbicidal properties were synthesized by cyclization of 2-amino-2,3-dimethylbutyramide with heterocyclic ethyl dicarboxylates under mild conditions. The use of NaH as base leads to a significant increase in the reaction rate and allows the preparation of the target compounds in high yields.
topic Imidazolinones
herbicides
cyclization
sodium hydride
url http://www.mdpi.com/1420-3049/9/7/535/
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