Photodynamic Vaccination of BALB/c Mice for Prophylaxis of Cutaneous Leishmaniasis Caused by Leishmania amazonensis

Photodynamic Vaccination of BALB/c Mice for Prophylaxis of Cutaneous Leishmaniasis Caused by Leishmania amazonensis

Background: Photosensitizers (PS), like porphyrins and phthalocyanines (PC) are excitable by light to generate cytotoxic singlet oxygen and other reactive oxygen species in the presence of atmospheric O2. Photodynamic inactivation of Leishmania by this means renders them non-viable, but preserves th...

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Bibliographic Details
Main Authors: Sayonara M. Viana, Fabiana S. Celes, Laura Ramirez, Bala Kolli, Dennis K. P. Ng, Kwang P. Chang, Camila I. de Oliveira
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Microbiology
Subjects:
Leishmania
leishmaniasis
potosensitizer
phthalocyanine
uroporphyrin
photodynamic vaccination
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00165/full

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