Femtograms of Interferon-γ Suffice to Modulate the Behavior of Jurkat Cells: A New Light in Immunomodulation

Femtograms of Interferon-γ Suffice to Modulate the Behavior of Jurkat Cells: A New Light in Immunomodulation

Since interferon-γ (IFN-γ) tunes both innate and adaptive immune systems, it was expected to enter clinical practice as an immunomodulatory drug. However, the use of IFN-γ has been limited by its dose-dependent side effects. Low-dose medicine, which is emerging as a novel strategy to treat diseases,...

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Bibliographic Details
Main Authors: Sara Castiglioni, Vincenzo Miranda, Alessandra Cazzaniga, Marilena Campanella, Michele Nichelatti, Marco Andena, Jeanette A. M. Maier
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:International Journal of Molecular Sciences
Subjects:
interferon-γ
Jurkat cells
immunomodulation
STAT-1
SOCS-1
Online Access:https://www.mdpi.com/1422-0067/18/12/2715

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