A mathematical modelling framework for the regulation of intra-cellular OCT4 in human pluripotent stem cells

A mathematical modelling framework for the regulation of intra-cellular OCT4 in human pluripotent stem cells

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Human pluripotent stem cells (hPSCs) have the potential to differentiate into all cell types, a property known as pluripotency. A deeper understanding of how pluripotency is regulated is required to assist in controlling pluripotency and differentiation trajectories experimentally. Mathematical mode...

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Bibliographic Details
Main Authors: L. E. Wadkin, S. Orozco-Fuentes, I. Neganova, M. Lako, N. G. Parker, A. Shukurov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336844/?tool=EBI

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