lncRNA PRR34-AS1 promotes HCC development via modulating Wnt/β-catenin pathway by absorbing miR-296-5p and upregulating E2F2 and SOX12

Hepatocellular carcinoma (HCC) belongs to the most frequent cancer with a high death rate worldwide. Thousands of long non-coding RNAs (lncRNAs) have been confirmed to influence the development of human cancers, including HCC. Nevertheless, the biological role of PRR34 antisense RNA 1 (PRR34-AS1) in...

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Bibliographic Details
Main Authors: Minzhen Qin, Yiliang Meng, Chunying Luo, Shougao He, Fengxue Qin, Yixia Yin, Junling Huang, Hailiang Zhao, Jing Hu, Zhihua Deng, Yiying Qiu, Gaoyu Hu, Hanhe Pan, Zongshuai Qin, Zansong Huang, Tingzhuang Yi
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121001104