Mechanistic Studies of the Anti-Ulcerogenic Activity and Acute Toxicity Evaluation of Dichlorido-Copper(II)-4-(2-5-Bromo-benzylideneamino)ethyl) Piperazin-1-ium Phenolate Complex against Ethanol-Induced Gastric Injury in Rats

Mechanistic Studies of the Anti-Ulcerogenic Activity and Acute Toxicity Evaluation of Dichlorido-Copper(II)-4-(2-5-Bromo-benzylideneamino)ethyl) Piperazin-1-ium Phenolate Complex against Ethanol-Induced Gastric Injury in Rats

The compound dichlorido-copper(II)-4-(2-5-bromobenzylideneamino)ethyl) piperazin-1-ium phenolate (CuLBS) was synthesized, characterized and screened for acute toxicity and protective activity against ethanol-induced gastric mucosal injury in rats. Gross microscopic lesions, biochemical and immunolog...

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Bibliographic Details
Main Authors: A. Hamid A. Hadi, Hapipah Mohd Ali, Mahmood Ameen Abdullah, Siddig Ibrahim Abdelwahab, Pouya Davish Hussain, Muhammad Saleh Salga
Format: Article
Language:English
Published: MDPI AG 2011-10-01
Series:Molecules
Subjects:
Schiff bases
acute toxicity
anti-ulcer activity
mechanism
cytokines
Online Access:http://www.mdpi.com/1420-3049/16/10/8654/

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http://www.mdpi.com/1420-3049/16/10/8654/

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