Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline

Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline

A series of oxazole and thereof imidazole derivatives were prepared from 2-chloro-7-methyl-3-formyl quinoline. The structures of all synthesized compounds were elucidated by elemental, IR, 1HNMR, 13CNMR spectra. Supplementary to these, they were assayed in vitro for their antimicrobial activity; it...

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Main Authors: R. H. Parab, B. C. Dixit
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2012/164235
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spelling doaj-2e1f0acbddc240349e84ee7c995fac092020-11-24T22:05:06ZengHindawi LimitedE-Journal of Chemistry0973-49452090-98102012-01-01931188119510.1155/2012/164235Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinolineR. H. Parab0B. C. Dixit1Chemistry Department, V.P. & R.P.T.P Science College, Vallabh Vidyanagar-388120, IndiaChemistry Department, V.P. & R.P.T.P Science College, Vallabh Vidyanagar-388120, IndiaA series of oxazole and thereof imidazole derivatives were prepared from 2-chloro-7-methyl-3-formyl quinoline. The structures of all synthesized compounds were elucidated by elemental, IR, 1HNMR, 13CNMR spectra. Supplementary to these, they were assayed in vitro for their antimicrobial activity; it was revealed that some synthesized derivatives were exhibiting competent biological activity against both gram negative and gram positive bacterial species and fungal microorganisms.http://dx.doi.org/10.1155/2012/164235
collection DOAJ
language English
format Article
sources DOAJ
author R. H. Parab
B. C. Dixit
spellingShingle R. H. Parab
B. C. Dixit
Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline
E-Journal of Chemistry
author_facet R. H. Parab
B. C. Dixit
author_sort R. H. Parab
title Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline
title_short Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline
title_full Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline
title_fullStr Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline
title_full_unstemmed Synthesis, Characterization and Antimicrobial Activity of Imidazole Derivatives Based on 2-chloro-7-methyl-3-formylquinoline
title_sort synthesis, characterization and antimicrobial activity of imidazole derivatives based on 2-chloro-7-methyl-3-formylquinoline
publisher Hindawi Limited
series E-Journal of Chemistry
issn 0973-4945
2090-9810
publishDate 2012-01-01
description A series of oxazole and thereof imidazole derivatives were prepared from 2-chloro-7-methyl-3-formyl quinoline. The structures of all synthesized compounds were elucidated by elemental, IR, 1HNMR, 13CNMR spectra. Supplementary to these, they were assayed in vitro for their antimicrobial activity; it was revealed that some synthesized derivatives were exhibiting competent biological activity against both gram negative and gram positive bacterial species and fungal microorganisms.
url http://dx.doi.org/10.1155/2012/164235
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AT bcdixit synthesischaracterizationandantimicrobialactivityofimidazolederivativesbasedon2chloro7methyl3formylquinoline
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