Kinetic Targeting of pegylated liposomal Doxorubicin: a new Approach to Reduce Toxicity during Chemotherapy (CARL-trial)

<p>Abstract</p> <p>Background</p> <p>The therapeutic success of chemotherapeutic agents is often limited by severe adverse effects. To reduce toxicity of these drugs, nanoscale particle-based drug delivery systems (DDS) are used. DDS accumulate to some extent in tumor t...

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Bibliographic Details
Main Authors: Jansen Martin, Hasenburg Annette, Rautenberg Beate, Zschiedrich Stefan, Groh Ursula, Siebers Jan W, Schmah Oliver, Eckes Jürgen, Hug Martin J, Winkler Karl, Pütz Gerhard
Format: Article
Language:English
Published: BMC 2011-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/337