Dabrafenib and Trametinib Treatment for Erdheim-Chester Disease With Brain Stem Involvement

Dabrafenib and Trametinib Treatment for Erdheim-Chester Disease With Brain Stem Involvement

Erdheim-Chester disease (ECD) is a rare form of non–Langerhans cell histiocytosis characterized by infiltration of organs by CD68+ and CD1a− lipid-laden histiocytes, including the central nervous system in more than a third of patients. Molecular analysis of ECD samples has demonstrated the prevalen...

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Bibliographic Details
Main Authors: Ahmed Al Bayati, MD, Thomas Plate, MD, Mahmood Al Bayati, BS, Yaohong Yan, MD, Efrat Saraf Lavi, MD, Joseph D. Rosenblatt, MD
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Online Access:http://www.sciencedirect.com/science/article/pii/S2542454818300341

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