Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation

Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation

NOBINs and other axially chiral entities have received a great deal of interest in recent years. Here, the authors report the kinetic resolution of racemic amino phenols and the enantioselective preparation of axially chiral N-aryl sulfonamides with excellent level of enantiopurity and broad substra...

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Bibliographic Details
Main Authors: Shenci Lu, Shawn Voon Hwee Ng, Kaitlyn Lovato, Jun-Yang Ong, Si Bei Poh, Xiao Qian Ng, László Kürti, Yu Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10940-4

Internet

https://doi.org/10.1038/s41467-019-10940-4

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