Mutational profiling of POT1 gene and its interaction with TPP1 in cancer- A computational approach

Mutational profiling of POT1 gene and its interaction with TPP1 in cancer- A computational approach

Telomeres are specialized structures at the end of eukaryotic chromosomes that maintain genomic stability by preventing chromosomal rearrangements and thereby enabling semi-conservative replication of telomeric DNA. The length of telomeric DNA is retained by telomerase that balances between the proc...

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Bibliographic Details
Main Authors: Priyanjali Bhattacharya, Pavan Kumar Dhanyamraju, Ankita Sarmah, Mohana Priya Jay, Chris Maria Jose, Sayali Dbritto, Showmeya Mallavarapu, Trupti N. Patel
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Informatics in Medicine Unlocked
Subjects:
SNPs
Telomeres
POT1variants
TPP1 gene
POT1-TPP1 interaction
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914820302215

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