Dynamics of Polarized Macrophages and Activated CD8+ Cells in Heart Tissue of Atlantic Salmon Infected With Piscine Orthoreovirus-1

Dynamics of Polarized Macrophages and Activated CD8+ Cells in Heart Tissue of Atlantic Salmon Infected With Piscine Orthoreovirus-1

Piscine orthoreovirus (PRV-1) infection causes heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). The virus is also associated with focal melanized changes in white skeletal muscle where PRV-1 infection of macrophages appears to be important. In this study, we stu...

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Bibliographic Details
Main Authors:	Muhammad Salman Malik, Ingvild Berg Nyman, Øystein Wessel, Maria K. Dahle, Espen Rimstad
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-09-01
Series:	Frontiers in Immunology
Subjects:	Atlantic salmon cell mediated immunity heart and skeletal muscle inflammation macrophage polarization Piscine orthoreovirus 1
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.729017/full

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