Regulation of STIM1 and SOCE by the ubiquitin-proteasome system (UPS).

The ubiquitin proteasome system (UPS) mediates the majority of protein degradation in eukaryotic cells. The UPS has recently emerged as a key degradation pathway involved in synapse development and function. In order to better understand the function of the UPS at synapses we utilized a genetic and...

Full description

Bibliographic Details
Main Authors: Jeffrey M Keil, Zhouxin Shen, Steven P Briggs, Gentry N Patrick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2956693?pdf=render