Expression of multiple transgenes from a single construct using viral 2A peptides in Drosophila.
Expression of multiple reporter or effector transgenes in the same cell from a single construct is increasingly necessary in various experimental paradigms. The discovery of short, virus-derived peptide sequences that mediate a ribosome-skipping event enables generation of multiple separate peptide...
Main Authors: | Richard W Daniels, Adam J Rossano, Gregory T Macleod, Barry Ganetzky |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4063965?pdf=render |
Similar Items
-
Use of the viral 2A peptide for bicistronic expression in transgenic mice
by: Trichas Georgios, et al.
Published: (2008-09-01) -
Loss of the Antimicrobial Peptide Metchnikowin Protects Against Traumatic Brain Injury Outcomes in Drosophila melanogaster
by: Laura C. Swanson, et al.
Published: (2020-09-01) -
Effects of Transgenic Expression of Botulinum Toxins in Drosophila
by: Backhaus, Philipp
Published: (2016) -
A Drosophila model to investigate the neurotoxic side effects of radiation exposure
by: Lisa J. Sudmeier, et al.
Published: (2015-07-01) -
A Drosophila toolkit for the visualization and quantification of viral replication launched from transgenic genomes.
by: Mathias F Wernet, et al.
Published: (2014-01-01)