Phytol supplementation alters plasma concentrations of formate, amino acids, and lipid metabolites in sheep

Phytol supplementation alters plasma concentrations of formate, amino acids, and lipid metabolites in sheep

The phytol moiety in chlorophyll molecules acts as an agonist of peroxisome proliferator-activated receptor-α in monogastric animals. The current study aimed to clarify the effects of dietary supplementation with phytol on the plasma concentrations of formate and amino acids related to one-carbon (1...

Full description

Bibliographic Details
Main Authors:	L.L. Ding, M. Matsumura, T. Obitsu, T. Sugino
Format:	Article
Language:	English
Published:	Elsevier 2021-03-01
Series:	Animal
Subjects:	Methionine cycle One-carbon donor Peroxisome proliferator-activated receptor-α ligand Phytanic acid Serine
Online Access:	http://www.sciencedirect.com/science/article/pii/S1751731121000045

Similar Items

Effect of phytol in forage on phytanic acid content in cow’s milk
by: Renlong Lv, et al.
Published: (2021-10-01)

Phytanoyl-CoA hydroxylase: recognition of 3-methyl-branched acyl-CoAs and requirement for GTP or ATP and Mg2+ in addition to its known hydroxylation cofactors
by: Kathleen Croes, et al.
Published: (2000-04-01)

Effects of dietary phytol and phytanic acid in animals
by: Daniel Steinberg, et al.
Published: (1966-09-01)

Stereochemistry of the α-oxidation of 3-methyl-branched fatty acids in rat liver
by: Kathleen Croes, et al.
Published: (1999-04-01)

RP-HPLC-fluorescence analysis of aliphatic aldehydes: application to aldehyde-generating enzymes HACL1 and SGPL1
by: Serena Mezzar, et al.
Published: (2014-03-01)

Sexually dimorphic metabolism of branched-chain lipids in C57BL/6J mice
by: Barbara P. Atshaves, et al.
Published: (2004-05-01)

Serum Lipid, Amino Acid and Acylcarnitine Profiles of Obese Cats Supplemented with Dietary Choline and Fed to Maintenance Energy Requirements
by: Adronie Verbrugghe, et al.
Published: (2021-07-01)

Metabolism of phytol to phytanic acid in the mouse, and the role of PPARα in its regulation
by: J. Gloerich, et al.
Published: (2007-01-01)

Further studies on the substrate spectrum of phytanoyl-CoA hydroxylase
by: Veerle Foulon, et al.
Published: (2003-12-01)

Peroxisomal Disorders Diagnosis
by: J Gordon Millichap
Published: (1998-12-01)

Diverse captive non-human primates with phytanic acid-deficient diets rich in plant products have substantial phytanic acid levels in their red blood cells
by: Moser Ann B, et al.
Published: (2013-02-01)

A phytol-enriched diet induces changes in fatty acid metabolism in mice both via PPARα-dependent and -independent pathways
by: J. Gloerich, et al.
Published: (2005-04-01)

Metabolism of phytol-U-14C and phytanic acid-U-14C in the rat
by: Charles E. Mize, et al.
Published: (1966-09-01)

Advanced Diagnostic System and Introduction of Newborn Screening of Adrenoleukodystrophy and Peroxisomal Disorders in Japan
by: Nobuyuki Shimozawa, et al.
Published: (2021-08-01)

Synthesis of phytanic acid
by: Stuart Patton, et al.
Published: (1966-05-01)

Substitution of Arginine 120 in Human D-Amino Acid Oxidase Favors FAD-Binding and Nuclear Mistargeting
by: Giulia Murtas, et al.
Published: (2019-11-01)

The Refsum disease marker phytanic acid, a branched chain fatty acid, affects Ca2+ homeostasis and mitochondria, and reduces cell viability in rat hippocampal astrocytes
by: Stefan Kahlert, et al.
Published: (2005-02-01)

The Role of PPARs in Disease
by: Nicole Wagner, et al.
Published: (2020-10-01)

Organic petrography, Rock–Eval pyrolysis and biomarker geochemistry of Maastrichtian Gombe Formation, Gongola Basin, Nigeria
by: Ayoola Y. Jimoh, et al.
Published: (2019-08-01)

Zonificación molecular de yacimientos de edad eoceno y mioceno al norte de la cuenca del lago de Maracaibo
by: Jhoan José Urdaneta
Published: (2019-08-01)

Nutrient-dependent phosphorylation channels lipid synthesis to regulate PPARα
by: Anne P.L. Jensen-Urstad, et al.
Published: (2013-07-01)

Stereochemistry of the peroxisomal branched-chain fatty acid α- and β-oxidation systems in patients suffering from different peroxisomal disorders
by: S. Ferdinandusse, et al.
Published: (2002-03-01)

Effect of berberine on PPARα-NO signalling pathway in vascular smooth muscle cell proliferation induced by angiotensin IV
by: Hongmei Qiu, et al.
Published: (2017-01-01)

Lipidomic profiling reveals protective function of fatty acid oxidation in cocaine-induced hepatotoxicity
by: Xiaolei Shi, et al.
Published: (2012-11-01)

Peroxisome Proliferator-Activated Receptor Activation is Associated with Altered Plasma One-Carbon Metabolites and B-Vitamin Status in Rats
by: Vegard Lysne, et al.
Published: (2016-01-01)

Mechanisms Mediating the Regulation of Peroxisomal Fatty Acid Beta-Oxidation by PPARα
by: Mounia Tahri-Joutey, et al.
Published: (2021-08-01)

α-Difluoromethylornithine-Induced Cytostasis is Reversed by Exogenous Polyamines, Not by Thymidine Supplementation
by: Mervi T. Hyvönen, et al.
Published: (2021-05-01)

Molecular mechanisms of peroxisome proliferator-activated receptor signaling
by: Dowell, Paul T.
Published: (2012)

Linalool is a PPARα ligand that reduces plasma TG levels and rewires the hepatic transcriptome and plasma metabolome[S]
by: Hee-jin Jun, et al.
Published: (2014-06-01)

Attenuation of high-fat diet-induced fatty liver through PPARα activation by stevioside
by: Chang-Hao Jia, et al.
Published: (2019-06-01)

Effect of aerobic-resistance training on plasma level of Peroxisome proliferator 1α in patients after coronary artery bypass grafting: A clinical trial study
by: Azar Hamidi, et al.
Published: (2021-07-01)

Decreased expression of peroxisome proliferator-activated receptor alpha indicates unfavorable outcomes in hepatocellular carcinoma
by: Xiao YB, et al.
Published: (2018-06-01)

The influence of the branched-chain fatty acids pristanic acid and Refsum disease-associated phytanic acid on mitochondrial functions and calcium regulation of hippocampal neurons, astrocytes, and oligodendrocytes
by: Sabine Rönicke, et al.
Published: (2009-11-01)

Effects of cis-9,trans-11 and trans-10,cis-12 Conjugated Linoleic Acid, Linoleic Acid, Phytanic Acid and the Combination of Various Fatty Acids on Proliferation and Cytokine Expression of Bovine Peripheral Blood Mononuclear Cells
by: Sven Dänicke, et al.
Published: (2013-07-01)

Regulation of human Δ-6 desaturase gene transcription: identification of a functional direct repeat-1 element
by: Chongren Tang, et al.
Published: (2003-04-01)

Synthesis of long-chain polyunsaturated fatty acids in lactating mammary gland: role of Δ5 and Δ6 desaturases, SREBP-1, PPARα, and PGC-1
by: Maricela Rodriguez-Cruz, et al.
Published: (2006-03-01)

The acyl-CoA thioesterase I is regulated by PPARα and HNF4α via a distal response element in the promoter
by: Bikesh Dongol, et al.
Published: (2007-08-01)

Regulation of ABCA1 expression in human keratinocytes and murine epidermis
by: Yan J. Jiang, et al.
Published: (2006-10-01)

Magnolol Alleviates Inflammatory Responses and Lipid Accumulation by AMP-Activated Protein Kinase-Dependent Peroxisome Proliferator-Activated Receptor α Activation
by: Ye Tian, et al.
Published: (2018-02-01)

Peroxisome proliferator-activated receptors-alpha (PPAR-α) and chronic heart failure: Is there a reason to discuss the metabolic strategy of treatment?
by: I V Zhirov, et al.
Published: (2014-01-01)