Regulation of Polycystin-1 Function by Calmodulin Binding.

Regulation of Polycystin-1 Function by Calmodulin Binding.

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a common genetic disease that leads to progressive renal cyst growth and loss of renal function, and is caused by mutations in the genes encoding polycystin-1 (PC1) and polycystin-2 (PC2), respectively. The PC1/PC2 complex localizes to primary...

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Bibliographic Details
Main Authors: Nicholas Doerr, Yidi Wang, Kevin R Kipp, Guangyi Liu, Jesse J Benza, Vladimir Pletnev, Tengis S Pavlov, Alexander Staruschenko, Ashraf M Mohieldin, Maki Takahashi, Surya M Nauli, Thomas Weimbs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4999191?pdf=render

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http://europepmc.org/articles/PMC4999191?pdf=render

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