Molecular analysis of acute and chronic reactive astrocytes in the pilocarpine model of temporal lobe epilepsy

Astroglia, the most abundant glial cells in the mammalian central nervous system (CNS), are considered an emerging key player in seizure induction and progression. Although astrocytes undergo reactive gliosis in temporal lobe epilepsy (TLE) with dramatic morphological and molecular changes, specific...

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Bibliographic Details
Main Authors: Jerome Clasadonte, Lydie Morel, Camila M. Barrios-Camacho, Ming Sum R. Chiang, Jinhua Zhang, Lakshmanan Iyer, Philip G. Haydon, Yongjie Yang
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116300705