The Insulin Receptor Mediates Insulin’s Early Plasma Clearance by Liver, Muscle, and Kidney

The role of the insulin receptor in mediating tissue-specific insulin clearance in vivo has not been reported. Using physiologic insulin doses, we measured the initial clearance rate (first 5 min) of intravenously injected ([<sup>125</sup>I]Tyr<sup>A14</sup>)-insulin by muscl...

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Bibliographic Details
Main Authors: Rick I. Meijer, Eugene J. Barrett
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/9/1/37