The Effectiveness of Ketamine in Pediatric Acute Deafferentation Pain after Spinal Cord Injury

Deafferentation pain and allodynia commonly occur after spinal cord trauma, but its treatment is often challenging. The literature on effective therapies for pediatric deafferentation pain, especially in the setting of spinal cord injury, is scarce. We report the case of a 12-year-old patient with a...

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Main Authors: Devina G. Shiwlochan, Misty Shah, Khushboo Baldev, Donna-Ann Thomas, Maxime Debrosse
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/2020/8835292
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spelling doaj-2dc1e6c1011042dd96e5f8100ef31a392020-11-25T04:07:35ZengHindawi LimitedCase Reports in Anesthesiology2090-63822090-63902020-01-01202010.1155/2020/88352928835292The Effectiveness of Ketamine in Pediatric Acute Deafferentation Pain after Spinal Cord InjuryDevina G. Shiwlochan0Misty Shah1Khushboo Baldev2Donna-Ann Thomas3Maxime Debrosse4Department of Anesthesiology, Yale School of Medicine, New Haven, Connecticut, USADepartment of Anesthesiology, Yale School of Medicine, New Haven, Connecticut, USADepartment of Anesthesiology, Yale School of Medicine, New Haven, Connecticut, USADepartment of Anesthesiology, Yale School of Medicine, New Haven, Connecticut, USADepartment of Anesthesiology, Yale School of Medicine, New Haven, Connecticut, USADeafferentation pain and allodynia commonly occur after spinal cord trauma, but its treatment is often challenging. The literature on effective therapies for pediatric deafferentation pain, especially in the setting of spinal cord injury, is scarce. We report the case of a 12-year-old patient with acute allodynia after a gunshot injury to the spine. The pain was refractory to multiple analgesics, but resolved with ketamine, which also improved the patient’s physical function and quality of life, a trend that continued many months after the injury. We suggest that early initiation of ketamine may be effective for acute pediatric deafferentation pain secondary to spinal cord injury, as well as preventing chronic pain states in that population.http://dx.doi.org/10.1155/2020/8835292
collection DOAJ
language English
format Article
sources DOAJ
author Devina G. Shiwlochan
Misty Shah
Khushboo Baldev
Donna-Ann Thomas
Maxime Debrosse
spellingShingle Devina G. Shiwlochan
Misty Shah
Khushboo Baldev
Donna-Ann Thomas
Maxime Debrosse
The Effectiveness of Ketamine in Pediatric Acute Deafferentation Pain after Spinal Cord Injury
Case Reports in Anesthesiology
author_facet Devina G. Shiwlochan
Misty Shah
Khushboo Baldev
Donna-Ann Thomas
Maxime Debrosse
author_sort Devina G. Shiwlochan
title The Effectiveness of Ketamine in Pediatric Acute Deafferentation Pain after Spinal Cord Injury
title_short The Effectiveness of Ketamine in Pediatric Acute Deafferentation Pain after Spinal Cord Injury
title_full The Effectiveness of Ketamine in Pediatric Acute Deafferentation Pain after Spinal Cord Injury
title_fullStr The Effectiveness of Ketamine in Pediatric Acute Deafferentation Pain after Spinal Cord Injury
title_full_unstemmed The Effectiveness of Ketamine in Pediatric Acute Deafferentation Pain after Spinal Cord Injury
title_sort effectiveness of ketamine in pediatric acute deafferentation pain after spinal cord injury
publisher Hindawi Limited
series Case Reports in Anesthesiology
issn 2090-6382
2090-6390
publishDate 2020-01-01
description Deafferentation pain and allodynia commonly occur after spinal cord trauma, but its treatment is often challenging. The literature on effective therapies for pediatric deafferentation pain, especially in the setting of spinal cord injury, is scarce. We report the case of a 12-year-old patient with acute allodynia after a gunshot injury to the spine. The pain was refractory to multiple analgesics, but resolved with ketamine, which also improved the patient’s physical function and quality of life, a trend that continued many months after the injury. We suggest that early initiation of ketamine may be effective for acute pediatric deafferentation pain secondary to spinal cord injury, as well as preventing chronic pain states in that population.
url http://dx.doi.org/10.1155/2020/8835292
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