Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain

Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain

AMPA-type glutamate receptors (AMPARs) mediate fast excitatory neurotransmission and are selectively recruited during activity-dependent plasticity to increase synaptic strength. A prerequisite for faithful signal transmission is the positioning and clustering of AMPARs at postsynaptic sites. The me...

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Bibliographic Details
Main Authors: Jake F Watson, Hinze Ho, Ingo H Greger
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-03-01
Series:eLife
Subjects:
AMPA receptor
synapse
LTP
N-terminal domain
NTD
Online Access:https://elifesciences.org/articles/23024

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